A Simple Cobalt(II) Chloride Catalyzed N-Alkylation of Amines with Alcohols

作者:Midya Siba P; Mondal Akash; Begum Ayesha; Balaraman Ekambaram
来源:Synthesis (Germany), 2017, 49(17): 3957-3961.
DOI:10.1055/s-0036-1589064

摘要

<jats:p>A facile cobalt-catalyzed N-alkylation of amines with alcohols using inexpensive, commercially available CoCl2·6H2O is reported. Employing this readily available cobalt catalyst, a variety of amines with wide functional group tolerance were selectively alkylated under benign conditions.</jats:p>

  • 出版日期2017-9