A New Isochroman Derivative from the Endophytic Microsphaeropsis arundinis

作者：Qin, Shao-Huan; Zhao, Li-Xing; Yang, Ya-Bin; Hu, Ming; Ding, Zhong-Tao^*

来源：Chemistry of Natural Compounds, 2017, 53(5): 877-879.

DOI：10.1007/s10600-017-2145-6

• Microsphaeropsis arundinis
• isochroman
• antimicrobial activity

A new isochroman derivative, erythro-2-methyl-5-hydroxyphenylpropane-7,8-diol (1), and three known compounds including of (4S)-4,8-dihydroxy-3,4-dihydro-1(2H)-naphthalen-1-one (2), (4S)-4,6,8-trihydroxy-3,4-dihydro-1(2H)-naphthalen-1-one (3), and chrysogeside D (4), were isolated from Microsphaeropsis arundinis. Compounds 3 and 4 were first found in Microsphaeropsis. The antibacterial, antiphytopathogenic, and antioxidant activities of these compounds were evaluated. Compounds 1 and 4 inhibited Alternaria tenuissima, a pathogenic fungus causing root rot of Panax notoginseng with MICs at 64 mu g/mL, which showed the ecological function of the endophyte for its host plant.

• 出版日期2017-9
• 单位云南大学