An improved method for the synthesis of gamma-DDB

作者：Song Chuanjun; Zhao Peng; Hu Zhiqiang; Shi Shuai; Cui Yanmei; Chang Junbiao

来源：Bioorganic & Medicinal Chemistry Letters, 2010, 20(7): 2297-2298.

DOI：10.1016/j.bmcl.2010.01.166

• gamma-DDB
• Ullmann reaction
• Anhydride-linker
• Selective bromination

A mild and efficient method for the synthesis gamma-DDB has been developed through anhydride-linker assisted intramolecular Ullmann reaction. Highly regioselective bromination of differentially protected gallate was realized by virtue of the introduction of NBS.

• 出版日期2010-4-1
• 单位郑州大学