Modelling continuous pharmaceutical and bio-based processes at plant-wide level: A roadmap towards efficient decision-making

作者：Ramin Pedram^*; Mansouri Seyed Soheil; Udugama Isuru A.; Benyahia Brahim; Gernaey Krist V

来源：Chimica Oggi-Chemistry Today, 2018, 36(2): 26-+.

• Continuous pharmaceutical production
• modelling benchmark
• PAT

The importance of developing simulation models for decision-making in pharmaceutical and bio-based production processes is elaborated in this article. The advantages of modelling continuous processes are outlined and certain barriers in this regard are identified. Although there have been some advancements in the field, there needs to be a larger international collaboration in this regard for providing reliable data for model validation, for development of generic model-based frameworks and implementing them in computer-aided platforms in the form of software tools.

• 出版日期2018-4