An electrochemical biosensor for detection of the sepsis-related biomarker procalcitonin

作者:Lim Jong Min; Ryu Myung Yi; Kim Ji Hong; Cho Chae Hwan; Park Tae Jung; Park Jong Pil*
来源:RSC Advances, 2017, 7(58): 36562-36565.
DOI:10.1039/c7ra06553a

摘要

An electrochemical peptide sensor employing a sensitive synthetic peptide was designed for the diagnosis of sepsis. A series of synthetic peptides were chemically synthesized, and the binding events and performance of the sensor were monitored by CV and EIS. PCT BP3, selected as a potential high-affinity peptide, was found to have a K-d value of 0.39 +/- 0.11 nM for procalcitonin.

  • 出版日期2017