Bladder cancer index: cross-cultural adaptation into Spanish and psychometric evaluation

作者：Schmidt Stefanie; Riel Ricard; Frances Albert; Lorente Garin Jose Antonio; Bonfill Xavier; Jose Martinez Zapata Maria; Morales Suarez Varela Maria; dela Cruz Javier; Ignacio Emparanza Jose; Sanchez Maria Jose; Zamora Javier; Ramos Goni Juan Manuel; Alonso Jordi; Ferrer Montse^*

来源：Health and Quality of Life Outcomes, 2014, 12(1): 20.

DOI：10.1186/1477-7525-12-20

• Urinary bladder neoplasms
• Quality of life
• Patient outcomes
• Validation studies
• Psychometrics

Background: The Bladder Cancer Index (BCI) is so far the only instrument applicable across all bladder cancer patients, independent of tumor infiltration or treatment applied. We developed a Spanish version of the BCI, and assessed its acceptability and metric properties. %26lt;br%26gt;Methods: For the adaptation into Spanish we used the forward and back-translation method, expert panels, and cognitive debriefing patient interviews. For the assessment of metric properties we used data from 197 bladder cancer patients from a multi-center prospective study. The Spanish BCI and the SF-36 Health Survey were self-administered before and 12 months after treatment. Reliability was estimated by Cronbach%26apos;s alpha. Construct validity was assessed through the multi-trait multi-method matrix. The magnitude of change was quantified by effect sizes to assess responsiveness. %26lt;br%26gt;Results: Reliability coefficients ranged 0.75-0.97. The validity analysis confirmed moderate associations between the BCI function and bother subscales for urinary (r = 0.61) and bowel (r = 0.53) domains; conceptual independence among all BCI domains (r %26lt;= 0.3); and low correlation coefficients with the SF-36 scores, ranging 0.14-0.48. Among patients reporting global improvement at follow-up, pre-post treatment changes were statistically significant for the urinary domain and urinary bother subscale, with effect sizes of 0.38 and 0.53. %26lt;br%26gt;Conclusions: The Spanish BCI is well accepted, reliable, valid, responsive, and similar in performance compared to the original instrument. These findings support its use, both in Spanish and international studies, as a valuable and comprehensive tool for assessing quality of life across a wide range of bladder cancer patients.

• 出版日期2014-2-15