N-(2-Methyl-5-tert-butyl-phenyl)-N-tert-butyl-nitroxide, a new thermally stable nitroxide

作者：Marx Lucien^*; Rassat Andre

来源：Tetrahedron Letters, 2015, 56(14): 1762-1763.

DOI：10.1016/j.tetlet.2014.12.119

• Nitroxides
• Hydroxylamines
• Decomposition

Quenching with tert-butyl nitroso 2-lithio-4-tert-butyl toluene prepared by an exchange reaction with t-butyl-lithium, followed by acidic hydrolysis furnishes in good yields the corresponding aromatic hydroxylamine whose oxidation affords the nitroxide, N-(2-methyl-5-tert-butyl-phenyl)-N-tert-butyl-nitroxide. This nitroxide did not undergo decomposition after heating 17 h in solution at 105 degrees C.

• 出版日期2015-4-1