A gram scale synthesis of a multi-C-13-labelled anthocyanin, [6,8,10,3 ',5 '-C-13(5)]cyanidin-3-glucoside, for use in oral tracer studies in humans

作者：Zhang Qingzhi; Botting Nigel P; Kay Colin

来源：Chemical Communications, 2011, 47(38): 10596-10598.

DOI：10.1039/c1cc14323a

The major dietary anthocyanin, cyanidin-3-glucoside, was prepared on a 4 g scale from three units of diethyl [2-C-13] malonate and one unit of [1,3-C-13(2)]acetone, such that five isotope locations were distributed throughout the molecule to provide a penta-C-13(5)-labelled anthocyanin, [6,8,10,3 ',5 '-C-13(5)]cyanidin-3-glucoside chloride, for use in human stable-isotope tracer studies.

• 出版日期2011