Antigenic variation in African trypanosomes: monitoring progress

作者：McCulloch R^*

来源：Trends in Parasitology, 2004, 20(3): 117-121.

DOI：10.1016/j.pt.2003.12.004

Antigenic variation is central to the success of African trypanosomes and other eukaryotic, bacterial and viral pathogens. Our understanding of the control and execution of this immune evasion strategy in trypanosomes is incomplete, despite the molecular basis of antigenic variation being first described over 20 years ago. Recent research progress in this field is highlighted here and some of the unresolved questions raised.

• 出版日期2004-3