Ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage after different treatments

作者：Wang, Sida; Liao, Chunyan; Liang, Shuyuan; Zhong, Danni; Liu, Junjie; Li, Zhixian^*

来源：International Journal of Clinical and Experimental Medicine, 2015, 8(4): 5085-5093.

• Periventricular-intraventricular hemorrhage
• Gesell Development Diagnosis Scale
• neonatal
• ultrasound

Objective: To investigate the ultrasound findings of mild neonatal periventricular-intraventricular hemorrhage (PIVH) after different treatments, and to evaluate the neurological outcomes of mild PIVH with Gesell Development Diagnosis Scale (GDDS). Methods: A total of 194 newborns with grade I-II PIVH were recruited, and findings of cranial ultrasound examination before and 1 month after birth were included for analysis. The echo intensity and size of the lesions were recorded. Results: There was no significant difference in the echo intensity among three groups of grade I PIVH patients (P>0.05). There was significant difference in the echo intensity among three groups of grade II PIVH patients, and the ganglioside had the best therapeutic efficacy (P<0.05). No significant difference was observed in the area change among three groups of grade I PIVH patients (P>0.05). However, significant difference was observed in the area change among three groups of grade II PIVH patients, and ganglioside had a better efficacy than cerebrolysin and control agent (P<0.05), but there was no significant difference between cerebrolysin and control groups (P>0.05). GDDS evaluation showed no significant difference among three groups (P>0.05), and all the patients recovered completely. Conclusion: The efficacy of different treatments for mild PIVH can be reflected in the ultrasound findings. Mild PIVH children generally have a good neurological prognosis.

• 出版日期2015
• 单位广西医科大学