Mining Genes in Type 2 Diabetic Islets and Finding Gold

作者：Eizirik Decio L^*; Cnop Miriam

来源：Cell Metabolism, 2012, 16(5): 555-557.

DOI：10.1016/j.cmet.2012.10.012

Pancreatic beta cell failure is central in the pathogenesis of type 2 diabetes (T2D), but the mechanisms involved remain unclear. Mahdi and colleagues (2012) couple global evaluation of gene expression with coexpression network analysis of human islets from T2D patients to identify SFRP4 as an early mediator of beta cell dysfunction in T2D.

• 出版日期2012-11-7