科研之友
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摘要
Portal imaging has become an integral part of modern radiotherapy techniques such as IMRT and IGRT. It serves to verify the accuracy of day-to-day patient positioning, a prerequisite for treatment success. However, image blurring attributable to different physical and geometrical effects, analysed in this work, impairs the image quality of the portal images, and anatomical structures cannot always be clearly outlined. A 2D iterative deconvolution method was developed to reduce this image blurring. The affiliated data basis was generated by the separate measurement of the components contributing to image blurring. Secondary electron transport and pixel size within the EPID, as well as geometrical penumbra due to the finite photon source size were found to be the major contributors, whereas photon scattering in the patient is less important. The underlying line-spread kernels of these components were shown to be Lorentz functions. This implies that each of these convolution kernels and also their combination can be characterized by a single characteristic, the width parameter lambda of the Lorentz function. The overall resulting lambda values were 0.5 mm for 6 MV and 0.65 mm for 15 MV. Portal images were deconvolved using the point-spread function derived from the Lorentz function together with the experimentally determined is lambda values. The improvement of the portal images was quantified in terms of the modulation transfer function of a bar pattern. The resulting clinical images show a clear enhancement of sharpness and contrast.
- 出版日期2011
