Assessment of tumor size as a useful marker for the surgical staging of endometrial cancer

作者：Berretta Roberto; Patrelli Tito Silvio; Migliavacca Costanza; Rolla Martino; Franchi Laura; Monica Michela; Modena Alberto Bacchi; Gizzo Salvatore^*

来源：Oncology Reports, 2014, 31(5): 2407-2412.

DOI：10.3892/or.2014.3108

• endometrial cancer
• tumor volume size
• pelvic lymphadenectomy
• tumor markers
• prognostic factors

Accumulating evidence suggests that the estimation of tumor size may improve endometrial cancer treatment. We conducted an observational study aimed at elucidating the association between tumor size and other universally accepted prognostic factors in order to identify suitable preoperative parameters which can guide surgery in a subgroup of early corpus endometrial cancer. We found that when tumor size increased, both stage and grading were significantly increased. Tumor size was correlated with CA 125 serum values, node metastasis and peritoneal cytology status. Patients who have grade 1 or 2 endometrioid corpus cancer, myometrial invasion %26lt;50% and %26lt;= 3 cm largest tumor diameter can only be treated with hysterectomy. The tumor largest diameter should be evaluated as a preoperative parameter that indicates patients who do not require lymphadenectomy.

• 出版日期2014-5