DMAP Promoted Tandem Addition Reactions Forming Substituted Tetrahydroxanthones

作者：Castillo Contreras Emmanuel B; Dake Gregory R^*

来源：Organic Letters, 2014, 16(6): 1642-1645.

DOI：10.1021/ol5002945

Substituted tetrahydroxanthones are constructed using a DMAP-promoted tandem nucleophilic addition process. The reaction yields range from 39% to 73%. Disubstituted tetrahydroxanthones are generated as a similar to 2.3:1 mixture of diastereomers favoring the formation of the trans-isomer.

• 出版日期2014-3-21