Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery

作者:Lanin Aleksandr A; Fedotov Il' ya V; Sidorov Biryukov Dmitrii A; Doronina Amitonova Lyubov V; Ivashkina Olga I; Zots Marina A; Sun Chi Kuang; Ilday F Omer; Fedotov Andrei B; Anokhin Konstantin V; Zheltikov Aleksei M*
来源:Applied Physics Letters, 2012, 100(10): 101104.
DOI:10.1063/1.3681777

摘要

Large-core hollow photonic- crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15-mu m-core hollow PCF compresses 510-fs, 1070-nm light pulses to a pulse width of about 110 fs, providing a peak power in excess of 5 MW. The compressed PCF output is employed to induce a local photodisruption of corpus callosum tissues in mouse brain and is used to generate the third harmonic in brain tissues, which is captured by the PCF and delivered to a detector through the PCF cladding.

  • 出版日期2012-3-5