An Efficient Procedure for the Synthesis of Hantzsch 1,4-Dihydropyridines Under Mild Conditions

作者：Ghorbani Choghamarani Arash^*; Zolfigol Mohammad Ali; Salehi Peyman; Ghaemi Ezat; Madrakian Elaheh; Nasr Isfahani Hossein; Shahamirian Mozhjgan

来源：Acta Chimica Slovenica, 2008, 55(3): 644-647.

• 1,4-Dihydropyridines
• ethyl propiolate
• methyl acetoacetate
• ammonium acetate
• solvent-free conditions

A simple and efficient one-pot synthesis of 1,4-dihydropyridine derivatives was achieved via condensation of methyl acetoacetate or ethyl propiolate with various alkyl and aryl aldehydes and ammonium acetate at 80 degrees C under solvent free conditions with good to excellent yields.

• 出版日期2008