Novel Mutations in K13 Propeller Gene of Artemisinin-Resistant Plasmodium falciparum

作者:Isozumi Rie*; Uemura Haruki; Kimata Isao; Ichinose Yoshio; Logedi John; Omar Ahmeddin H; Kaneko Akira
来源:Emerging Infectious Diseases, 2015, 21(3): 490-492.
DOI:10.3201/eid2103.140898

摘要

We looked for mutations in the Plasmodium falciparum K13 propeller gene of an artemisinin-resistant parasite on islands in Lake Victoria, Kenya, where transmission in 2012-2013 was high. The 4 new types of nonsynonymous, and 5 of synonymous, mutations we detected among 539 samples analyzed provide clues to understanding artemisinin-resistant parasites.

  • 出版日期2015-3