摘要
Procaine and benzocaine are used as local anaesthetic agents used in so called "small surgery". Even if in numerous fields they were replaced by newer molecules, certain medical fields continue their use under some circumstances. This study is focused on the synthesis of procaine from its precursor benzocaine using a green chemistry synthesis, namely "solvent-free" synthesis in the presence of an alternative source of energy- microwave irradiation. In our study, we have managed to convert quantitatively benzocaine to procaine in a short period of time (12 min) over microwave irradiation (700W).
- 出版日期2014-1