Advances in the generation of bioengineered bile ducts

作者：Justin Alexander W^*; Saeb Parsy Kourosh; Markaki Athina E; Vallier Ludovic; Sampaziotis Fotios^*

来源：Biochimica et Biophysica Acta-Molecular Basis of Disease, 2018, 1864(4): 1532-1538.

DOI：10.1016/j.bbadis.2017.10.034

• Bile duct
• Tissue engineering
• Bioengineering
• Cholangiopathy

The generation of bioengineered biliary tissue could contribute to the management of some of the most impactful cholangiopathies associated with liver transplantation, such as biliary atresia or ischemic cholangiopathy. Recent advances in tissue engineering and in vitro cholangiocyte culture have made the achievement of this goal possible. Here we provide an overview of these developments and review the progress towards the generation and transplantation of bioengineered bile ducts. This article is part of a Special Issue entitled: Cholangiocytes in Health and Disease edited by Jesus Banales, Marco Marzioni and Peter Jansen.

• 出版日期2018-4