Timing of Influenza A(H5N1) in Poultry and Humans and Seasonal Influenza Activity Worldwide, 2004-2013

作者：Durand Lizefte O; Glew Patrick; Gross Diane; Kasper Matthew; Trock Susan; Kim Inkyu K; Bresee Joseph S; Donis Ruben; Uyeki Timothy M; Widdowson Marc Alain; Azziz Baumgartner Eduardo^*

来源：Emerging Infectious Diseases, 2015, 21(2): 202-208.

DOI：10.3201/eid2102.140877

Co-circulation of influenza A(H5N1) and seasonal influenza viruses among humans and animals could lead to coinfections, reassortment, and emergence of novel viruses with pandemic potential. We assessed the timing of subtype H5N1 outbreaks among poultry, human H5N1 cases, and human seasonal influenza in 8 countries that reported 97% of all human H5N1 cases and 90% of all poultry H5N1 outbreaks. In these countries, most outbreaks among poultry (7,001/11,331, 62%) and half of human cases (313/625, 50%) occurred during January March. Human H5N1 cases occurred in 167 (45%) of 372 months during which outbreaks among poultry occurred, compared with 59 (10%) of 574 months that had no outbreaks among poultry. Human H5N1 cases also occurred in 59 (22%) of 267 months during seasonal influenza periods. To reduce risk for co-infection, surveillance and control of H5N1 should be enhanced during January March, when H5N1 outbreaks typically occur and overlap with seasonal influenza virus circulation.

• 出版日期2015-2