科研之友
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摘要
Background The Animals in Research: Reporting In Vivo Experiments (ARRIVE) guidelines were published in 2010 with the aim of improving the quality of studies involving animals. However, how well Chinese studies involving animal neoplasms adhere to these guidelines has not been assessed. Objective To evaluate the reporting quality of such experiments published between 2010 and 2012 in Chinese journals with support from the National Natural Science Foundation of China. Methods We searched the Chinese Science Citation and Chinese Journal Full-Text Databases for articles published between 2010 and 2012 involving neoplasms in animals. The data were extracted into pre-prepared forms. Reporting quality was assessed using the ARRIVE checklist-39 items plus information on blinding. Results Three hundred and ninety-six animal studies were included in the analysis: 127 studies published in 2010, 140 studies published in 2011, and 129 studies published in 2012. The range of ARRIVE score is from 12 to 27 with a maximum possible score of 40. Studies published in 2012 (P = 0.012), 2011 (P = 0.015), 2010, July similar to Dec (P<0.017) had a significantly larger ARRIVE checklist score than those published in Jan.similar to June, 2010, respectively. Conclusions Experiments involving neoplasms in animals published in Chinese journals generally have not comprehensively reported the information recommended by the ARRIVE guidelines. We strongly recommend that researchers conducting such studies report this information.
