摘要

Polyether ionophore antibiotics are a large group of natural substances, produced by various species of Streptomyces. These agents possess the ability to transport metal cations across lipid membranes, interfere with natural ion transport systems in cells and exhibit a variety of biological properties (antibacterial, antiparasitic, antiinflammatory or antiacancer). Several ionophores (e.g. lasalocid, monensin, narasin, salinomycin) are commercially applied as coccidiostatics in veterinary. The purpose of this report is to present an overview of antimicrobial activities of selected ionofores - lasalocid, monensin and salinomycin, and their derivatives.

  • 出版日期2015-6