An Efficient Synthesis of 5-Benzoyloxazolines by Regio- and Stereo-controlled Reaction of N-Substituted 2-Benzoylaziridines Under Microwave Irradiation

作者:Samimi Heshmat A; Mamaghani Manouchehr*; Tabatabaeian Khalil
来源:Journal of Heterocyclic Chemistry, 2008, 45(6): 1765-1770.
DOI:10.1002/jhet.5570450632

摘要

Several N-acyl-2-benzoylaziridines were prepared conveniently in good to high yields (71-93%) and used in the preparation of 5-benzoyloxazolines (76-91%) by a regio- and stereo-controlled reaction in the presence of NaI as an efficient catalyst under microwave irradiation in short reaction times (5-10 mins). The structure of the regioisomeric product was confirmed by X-ray analysis.

  • 出版日期2008-12