A naphthalene derivative as "turn-on' fluorescent chemosensor for the highly selective and sensitive detection of Al3+

作者：Zhu, Zhong-Xin; Yu, Dong-Dong; Liu, Zhi-Guo; Huang, Ye-Wei; Zhou, A-Yi; Chen, Zhi-Wei; Sun, Jia; Wang, Xu; Jin, Li-Tai^*; Cong, Wei-Tao^*

来源：Luminescence, 2017, 32(7): 1307-1312.

DOI：10.1002/bio.3326

• aluminum ion
• cell imaging
• fluorescent probe
• highly selective response

A Schiff base compound derived from naphthalene has been synthesized and characterized as an Al3+-selective fluorescent probe. The chemosensor (L) exhibits high selectively for Al3+ in aqueous solution, even in the presence of biologically relevant cations such as Na+, K+, Ca2+, Mg2+, Pb2+ and several transition metal ions. There was no observed interference from anions like Br-, Cl-, HSO3-, SO32-, S2O32-, NO2-, CO32- and AC(-). The lowest detection limit for the chemosensor L was found to be 1.89x10(-8)M with a linear response towards Al3+ over a concentration range of 5x10(-6) to 4x10(-5)M. Furthermore, the proposed chemosensor has been used for imaging of Al3+ in two different types of cells with satisfying results, which further demonstrates its value for practical application in biological systems.

• 出版日期2017-11
• 单位温州医科大学