A new "ON-OFF-ON" fluorescent probe for sequential detection of Fe3+ and PPi based on 2-pyridin-2-ylethanamine and benzimidazo [2,1-a]benz[de]isoquinoline-7-one-12-carboxylic acid

作者：Xu, Yuankang; Liu, Xiaogang; Zhao, Jinyan; Wang, Hanyu; Liu, Zheng; Yang, Xiaofeng; Pei, Meishan; Zhang, Guangyou^*

来源：New Journal of Chemistry, 2019, 43(1): 474-480.

DOI：10.1039/c8nj04870c

• RHODAMINE-BASED FLUORESCENT
• AQUEOUS-SOLUTION
• SCHIFF-BASE
• LIVING CELLS
• CHEMOSENSOR
• SENSOR
• IRON(III)
• CU2+
• ION
• IRON

A new fluorescent probe X based on 2-pyridin-2-ylethanamine and benzimidazo[2,1-a]benz[de]isoquinoline-7-one-12-carboxylic acid was designed and synthesized for the detection of Fe3+ and PPi. X showed high sensitivity and selectivity for Fe3+ in the presence of other competing metal ions in DMF/H2O buffer solution. The limit of detection for Fe3+ was calculated from the titration curve to be 6.7 x 10(-7) M. The Job's plot confirmed a 1:1 stoichiometry between the probe and Fe3+, and the complexation stability constant was calculated to be 7.46 x 10(3) M-1. Moreover, the fluorescence intensity of the probe was recovered after addition of the PPi. X could act as a fluorescence ON-OFF-ON probe for the sequential detection of Fe3+ and PPi. The binding mode and sensing mechanism of X with Fe3+ was verified by DFT/TDDFT calculations using Gaussian 09.

• 出版日期2019-1-7
• 单位济南大学; 哈尔滨工程大学