A simple method for fabricating microwire tetrode with sufficient rigidity and integrity without a heat-fusing process

作者:Liao Yi Fang; Tsai Meng Li; Yen Chen Tung; Cheng Chiung Hsiang*
来源:Journal of Neuroscience Methods, 2011, 195(2): 211-215.
DOI:10.1016/j.jneumeth.2010.12.017

摘要

Heat-fusing is a common process for fabricating microwire tetrodes. However, it is time-consuming, and the high-temperature treatment can easily cause the insulation of the microwire to overheat leading to short circuits. We herein provide a simple, fast method to fabricate microwire tetrodes without the heat-fusion process. By increasing the twisting density, we were able to fabricate tetrodes with good rigidity and integrity. This kind of tetrode showed good recording quality, penetrated the brain surface easily, and remained intact after chronic implantation. This method requires only general laboratory tools and is relatively simple even for inexperienced workers.

  • 出版日期2011-2-15