A case of Budd-Chiari syndrome: Gd-EOB-DTPA-enhanced MR findings

作者：Kitajima Kazuhiro; Yoshikawa Takeshi^*; Seo Yasushi; Ohno Yoshiharu; Yano Yoshihiko; Miki Akira; Kanda Tomonori; Kanata Naoki; Azuma Takeshi; Sugimura Kazuro

来源：Magnetic Resonance Imaging, 2011, 29(4): 579-583.

DOI：10.1016/j.mri.2010.10.013

• Budd-Chiari syndrome
• Liver-specific contrast medium
• Magnetic resonance imaging

Budd-Chiari syndrome (BCS) is a rare disorder caused by the obstruction of hepatic venous outflow, leading to sinusoidal congestion, ischemic injury to liver cells and portal hypertension. Long-term survival largely depends on whether hepatocellular carcinoma occurs. A recently available liver-specific contrast medium, gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid (Gd-EOB-DTPA), reportedly has high diagnostic capability for detection of malignant liver tumors. However, there has been no report of the sue of Gd-EOB-DTPA-enhanced magnetic resonance imaging (MRI) for BCS. We present a case of chronic BCS who underwent both gadopentetate dimeglumine (Gd-DTPA) and Gd-EOB-DTPA-enhanced MRI. Hepatic congestion and edema were seen as slightly hypointense area:. on Gd-EOB-DTPA-enhanced hepatobiliary-phase images, although these areas were observed as slightly hyperintense on previously obtained Gd-DTPA-enhanced delayed-phase image. Reduced uptake of Gd-EOB-DTPA by hepatocytes in the region of congestion or edema may account for this difference, which should be recognized in image interpretations.

• 出版日期2011-5