Neonatal seizure automatism and human inborn pattern of quadrupedal locomotion

作者：Pavlidis E^*; Cantalupo G; Cattani L; Tassinari C A; Pisani F

来源：Gait & Posture, 2016, 49: 232-234.

DOI：10.1016/j.gaitpost.2016.07.015

• Central pattern generators
• Newborn locomotion
• Inter-limb coordination
• Neonatal seizures
• Subtle seizures

Seizures in newborns do not always show a clear electro-clinical correlation. The real epileptic nature of some stereotyped rhythmic movements, included in the 'subtle seizures' and considered as brainstem release phenomena, is still debated. We report a brain injured newborn, who displayed several episodes of repetitive limb movements. The ictal EEG discharge, during one of these episodes, was associated with a motor pattern modification, which was endowed with quadrupedal locomotion kinematic features. This might represent an indirect evidence of cervical and lumbar central Pattern Generators interconnection with in-phase coordination between diagonal limbs since the first hours of life in humans.

• 出版日期2016-9