MRI of the Hip at 7T: Feasibility of Bone Microarchitecture, High-Resolution Cartilage, and Clinical Imaging

作者：Chang Gregory^*; Deniz Cem M; Honig Stephen; Egol Kenneth; Regatte Ravinder R; Zhu Yudong; Sodickson Daniel K; Brown Ryan

来源：Journal of Magnetic Resonance Imaging, 2014, 39(6): 1384-1393.

DOI：10.1002/jmri.24305

• 7T
• MRI
• hip
• bone microarchitecture
• cartilage
• clinical

PurposeTo demonstrate the feasibility of performing bone microarchitecture, high-resolution cartilage, and clinical imaging of the hip at 7T.
Materials and MethodsThis study had Institutional Review Board approval. Using an 8-channel coil constructed in-house, we imaged the hips of 15 subjects on a 7T magnetic resonance imaging (MRI) scanner. We applied: 1) a T1-weighted 3D fast low angle shot (3D FLASH) sequence (0.23 x 0.23 x 1-1.5 mm(3)) for bone microarchitecture imaging; 2) T1-weighted 3D FLASH (water excitation) and volumetric interpolated breath-hold examination (VIBE) sequences (0.23 x 0.23 x 1.5 mm(3)) with saturation or inversion recovery-based fat suppression for cartilage imaging; 3) 2D intermediate-weighted fast spin-echo (FSE) sequences without and with fat saturation (0.27 x 0.27 x 2 mm) for clinical imaging.
ResultsBone microarchitecture images allowed visualization of individual trabeculae within the proximal femur. Cartilage was well visualized and fat was well suppressed on FLASH and VIBE sequences. FSE sequences allowed visualization of cartilage, the labrum (including cartilage and labral pathology), joint capsule, and tendons.
ConclusionThis is the first study to demonstrate the feasibility of performing a clinically comprehensive hip MRI protocol at 7T, including high-resolution imaging of bone microarchitecture and cartilage, as well as clinical imaging. J. Magn. Reson. Imaging 2014;39:1384-1393.

• 出版日期2014-6