摘要

In this study, we explored the regioselective benzylation of L-glutamic acid under substoichiometric amounts of the alkylating agent. Our results demonstrate unambiguously that N,N-dibenzylglutamic acid gamma-benzyl ester was not obtained by direct benzylation of L-glutamic acid as reported by other authors. Instead, under such reaction conditions N,N-dibenzylglutamic acid alpha-benzyl ester was obtained.

  • 出版日期2014-9