New architectures in hydrogen bond catalysis

作者:Rodriguez Andrew A; Yoo Hoseong; Ziller Joseph W; Shea Kenneth J*
来源:Tetrahedron Letters, 2009, 50(49): 6830-6833.
DOI:10.1016/j.tetlet.2009.09.129

摘要

New achiral sulfamide, phosphoric triamide, and thiophosphoric triamide compounds have been synthesized. Their activity as hydrogen bond catalysts for the Friedel-Crafts and Baylis-Hillman reactions compares favorably with that of a known and an active thiourea catalyst. The new compounds were also studied by X-ray crystallography and their solid state structures are described.

  • 出版日期2009-12-9