Divergent Construction of Pyrazoles via Michael Addition of N-Arylhydrazones to 1,2-Diaza-1,3-dienes

作者：Mantenuto Serena; Mantellini Fabio; Favi Gianfranco^*; Attanasi Orazio A

来源：Organic Letters, 2015, 17(8): 2014-2017.

DOI：10.1021/acs.orglett.5b00776

The base (NaH)-promoted Michael addition of N-arylhydrazones (AHs) with 1,2-diaza-1,3-dienes (DDs) produces unprecedented beta-azohydrazone adducts. Strategically, the use of AHs as acyl anion equivalents (d(1) synthon) and DDs as a-electrophiles (a(2) synthon) of carbonyl compounds open the way to two important classes of pyrazole compounds

• 出版日期2015-4-17