A numerical method for optimizing laser power in the irradiation of a 3-D triple-layered cylindrical skin structure

作者:Zhang L; Dai WZ*; Nassar R
来源:Numerical Heat Transfer Part A-Applications, 2005, 48(1): 21-41.
DOI:10.1080/104077805909292865

摘要

It is of interest to research hyperthermia combined with radiation and cytotoxic drugs to enhance the killing of tumors. The crucial problem is to keep surrounding normal tissue below a temperature that will produce harm when heating the tumor tissue. In this study, we develop a numerical model for optimizing laser power in the irradiation of a 3-D triple-layered cylindrical skin structure. The method determines the required laser intensity in order to obtain prespecified temperatures at given locations on the skin surface after a prespecified laser exposure time.

  • 出版日期2005-7-1