An Efficient Synthesis of Novel Fused Cycloheptatrienes through Mn(II)-Mediated Formal Intermolecular [2+2+2+1] Cycloaddition

作者：Shu, Wen-Ming; Ma, Jun-Rui; Yang, Yan; Wu, An-Xin^*

来源：Organic Letters, 2014, 16(5): 1286-1289.

DOI：10.1021/ol500202q

• RHODIUM COMPLEXES
• ORGANIC-SYNTHESIS
• QUINONE METHIDES
• NATURAL-PRODUCTS
• METAL
• ALKYNES
• VINYLCYCLOPROPANES
• STRATEGY
• ESTER
• RINGS

A new method for manganous acetate tetrahydrate mediated formal intermolecular [2 + 2 + 2 + 1] cycloaddition was developed for the synthesis of fused cycloheptatriene derivatives from N-(acylmethyl)pyridinium iodides and naphthoquinone. This method provides an innovative route for the efficient and convenient construction of fused seven-membered carbocycles from simple starting materials.

• 出版日期2014-3-7
• 单位华中师范大学