Regioselective Reaction of Ethyl 5-Acetyl-3,4-dihydropyridine-1(2H)-carboxylate with Hydrazines: A Facile Approach to New Pyrazole Derivatives

作者：Maximov Nazar B; Mykhailiuk Pavel K^*; Golovach Sergey M; Tverdokhlebov Anton V; Voitenko Zoya V; Tolmachev Andrey A

来源：Synthesis, 2010, (11): 1781-1786.

DOI：10.1055/s-0029-1219760

• pyrazole
• hydrazine
• tetrahydropyridine
• regioselectivity

The reaction of ethyl 5-acetyl-3,4-dihydropyridine-1(2H)-carboxylate with diverse aliphatic as well as aromatic monosubstituted hydrazines resulted in the regioselective formation of N-substituted 3-methylpyrazoles.

• 出版日期2010-6