An Amylose-Poly(L-lactide) Inclusion Supramolecular Polymer: Enzymatic Synthesis by Means of Vine-Twining Polymerization Using a Primer-Guest Conjugate

作者：Tanaka Tomonari^*; Sasayama Shota; Nomura Shintaro; Yamamoto Kazuya; Kimura Yoshiharu; Kadokawa Jun ichi

来源：Macromolecular Chemistry and Physics, 2013, 214(24): 2829-2834.

DOI：10.1002/macp.201300525

• amylose
• phosphorylase
• polylactide
• supramolecular polymers
• vine-twining polymerization

An inclusion supramolecular polymer composed of amylose and poly(l-lactide) (PLLA) is successfully synthesized by phosphorylase-catalyzed enzymatic polymerization using a maltoheptaose-functionalized poly(l-lactide) (G(7)-PLLA) as a primer-guest conjugate substrate according to vine-twining polymerization. The product forms a polymeric continuum of an inclusion complex in which PLLA is included by an amylose chain enzymatically elongated from the other G(7)-PLLA. The product is characterized by powder X-ray diffraction, H-1 NMR spectroscopy, and gel-permeation chromatography measurements. The analytical results indicate that such an inclusion supramolecular polymer is efficiently produced, even under the low concentration of the guest polymer, PLLA, owing to the high local concentration of PLLA segments in the present system because G(7)-PLLA forms aggregates 50-110 nm in diameter in aqueous media.

• 出版日期2013-12