Layer-by-layer assembly of hemoglobin-coated microspheres for enhancing the oxygen carrying capacity

作者:Sun, Lijun; Lu, Yannan; Pan, Zhongqin; Wu, Tingting; Liu, Xiaojun; Bao, Ning; Yu, Chunmei; He, Hong*; Gu, Haiying*
来源:RSC Advances, 2016, 6(65): 59984-59987.
DOI:10.1039/c6ra05638e

摘要

Hemoglobin-coated microspheres with one layer and five layers were fabricated by layer-by-layer assembly. The electrochemical methods were used to study their capacity for carrying oxygen. The results provided direct evidences that microspheres with five-layer hemoglobin could store and release more oxygen than those with one layer. This study also provided an alternative method for evaluating the oxygen carrying capacity of hemoglobin microspheres.