Determination of the scattering coefficient of biological tissue considering the wavelength and absorption dependence of the anisotropy factor

作者：Fukutomi Daichi; Ishii Katsunori; Awazu Kunio

来源：Optical Review, 2016, 23(2): 291-298.

DOI：10.1007/s10043-015-0161-y

• Scattering coefficient
• Anisotropy factor
• Goniometry
• Integrating sphere
• Inverse Monte Carlo simulation

The anisotropy factor g, one of the optical properties of biological tissues, has a strong influence on the calculation of the scattering coefficient mu(s) in inverse Monte Carlo (iMC) simulations. It has been reported that g has the wavelength and absorption dependence; however, few attempts have been made to calculate mu(s) using g values by taking the wavelength and absorption dependence into account. In this study, the angular distributions of scattered light for biological tissue phantoms containing hemoglobin as a light absorber were measured by a goniometric optical setup at strongly (405 nm) and weakly (664 nm) absorbing wavelengths to obtain g. Subsequently, the optical properties were calculated with the measured values of g by integrating sphere measurements and an iMC simulation, and compared with the results obtained with a conventional g value of 0.9. The mu(s) values with measured g were overestimated at the strongly absorbing wavelength, but underestimated at the weakly absorbing wavelength if 0.9 was used in the iMC simulation.

• 出版日期2016-4