Application of carbon nanotube-ionic liquid-epinephrine composite gel modified electrode as a sensor for glutathione

作者：Liu, Benzhi^*; Wang, Min; Xiao, Bo

来源：Journal of Electroanalytical Chemistry, 2015, 757: 198-202.

DOI：10.1016/j.jelechem.2015.09.034

• Glutathione
• Carbon nanotube
• Ionic liquid
• Epinephrine
• Electrochemical sensor

A sensitive and convenient electrochemical sensor was developed for the determination of glutathione by using a carbon nanotube-ionic liquid-epinephrine composite gel modified electrode. As a mediator, epinephrine exhibited an obvious electrocatalytic activity towards the oxidation of glutathione. The square wave voltammetric technique was used to detect glutathione. The oxidation peak current showed a linear relationship with the concentration of glutathione in the range of 0.1-3.0 mu M, with a detection limit of 0.04 mu M. The repeatability and reproducibility of the sensor were investigated with the relative standard deviation (RSD%) 3.7% and 4.2%, respectively. The proposed sensor was successfully applied for the determination of glutathione in urine sample and tablet. Good recovery of 94%-106% demonstrated the capability of the sensor for the determination of GSH in real samples.

• 出版日期2015-11-15
• 单位盐城工学院