A new way of forming a calcium phosphate cement using bioactive glasses as a reactive precursor

作者：Kent Niall W; Hill Robert G; Karpukhina Natalia^*

来源：Materials Letters, 2016, 162: 32-36.

DOI：10.1016/j.matlet.2015.09.099

• Calcium phosphate cement
• Apatite cement
• Brushite cement
• Bioactive glass

Calcium phosphate cements (CPC)s are conventionally made by mixing crystalline calcium phosphates with aqueous solutions. In this study new CPCs are made by reacting bioactive glasses (BG)s with Ca (H2PO4)(2) to form cement. It is found that high P2O5 content of 4 mol% or greater is required in BG to produce a cement. The phases formed are dependent On glass composition; brushite and octacalcium phosphate (OCP) form first with 6 mol% P2O5 BG. Brushite dissolves, reforms as OCP, then transforms to apatite. These new cements offer new route to forming CPC that combine in-situ setting and injectability of CPCs with resorbability and bioactivity of BGs.

• 出版日期2016-1-1