Aqueous asymmetric aldol reaction catalyzed by nanomagnetic solid acid SO42-/Zr(OH)(4)-Fe3O4

作者：Wu Tao; Wan Jingwei; Ma Xuebing^*

来源：Chinese Journal of Catalysis, 2015, 36(3): 425-431.

DOI：10.1016/S1872-2067(14)60222-9

• Solid acid catalyst
• Magnetism
• Aldol reaction
• Asymmetric catalysis
• Aqueous phase

Magnetic solid acid catalysts SO42-/Zr(OH)(4)-Fe3O4 were prepared using magnetic Fe3O4 nanoparticles, ZrOCl2 center dot 8H(2)O, and sulfuric acid as starting materials in the calcination temperature range 110-650 degrees C. The properties of the magnetic solid acid, such as loaded SO42- content, acid distribution, surface morphology, and porous structure, were characterized. In the aqueous asymmetric aldol reaction of various benzaldehydes with strong electron-withdrawing groups (R = NO2 and CN), good to excellent catalytic performance (83%-100% yield, 86.0%-95.6% ee anti, and anti/syn = 88-96/12-4) was achieved. These nanomagnetic solid acids can be quantitatively recycled from the reaction mixture using an external magnet and reused five times without significant loss of catalytic activity.

• 出版日期2015-3
• 单位西南大学