A consensus approach to improving patient adherence and persistence with topical treatment for actinic keratosis

作者：Stockfleth Eggert^*; Peris Ketty; Guillen Carlos; Cerio Rino; Basset Seguin Nicole; Foley Peter; Sanches Jose; Culshaw Alex; Erntoft Sandra; Lebwohl Mark

来源：International Journal of Dermatology, 2015, 54(5): 509-515.

DOI：10.1111/ijd.12840

BackgroundTopical therapy is important in the treatment of actinic keratosis, but guidance for improving adherence/persistence during topical therapy is still lacking.
ObjectivesTo utilize expert consensus to generate a list of recommendations to improve real-world efficacy when prescribing topical therapy for actinic keratosis.
MethodsAn expert panel of eight dermatologists was convened to generate recommendations based on facilitated discussion and consensus generation using a modified Delphi session. The recommendations were ratified with the expert panel.
ResultsFacilitated discussion generated 31 issues within five themes, which were prioritized using expert voting. Consensus was achieved on the importance of short and simple treatment regimens for maximizing patient compliance, physician awareness of the progression of actinic keratosis to squamous cell carcinoma, provision of appropriate patient information, and the use of effective communication strategies to educate physicians about actinic keratosis. Based on these key findings, eight recommendations were generated.
ConclusionsThe recommendations will assist physicians when prescribing topical actinic keratosis therapy. Further research should focus on the types of patient outcomes that are influenced by the characteristics of topical field therapy.

• 出版日期2015-5