科研之友
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摘要
In the present study, we found a novel approach to the simple and practical synthesis of 3-aminopyrrole derivatives through the four-component coupling reaction of a functionalized silane, a nitrile, an aldehyde, and trimethylsilyl cyanide by Yb(OTf)(3)-catalyzed annulation of a 2-azabutadiene with trimethylsilyl cyanide In this paper, we also disclose a single-step transformation of the 3-aminopyrrole framework into the pyrrolo[3,4-b]pyridin-4-one skeleton
- 出版日期2010-8
