Mitochondrial Protection by Resveratrol

作者:Ungvari Zoltan*; Sonntag William E; de Cabo Rafael; Baur Joseph A; Csiszar Anna
来源:Exercise and Sport Sciences Reviews, 2011, 39(3): 128-132.
DOI:10.1097/JES.0b013e3182141f80

摘要

UNGVARI, Z., W. E. SONNTAG, R. DE CABO, J.A. BAUR, and A. CSISZAR. Mitochondrial protection by resveratrol. Exerc. Sport. Sci. Rev., Vol. 39, No. 3, pp. 128-132, 2011. Mitochondrial dysfunction and oxidative stress are thought to play important roles in mammalian aging. Resveratrol is a plant-derived polyphenol that exerts diverse antiaging activities, mimicking some of the molecular and functional effects of dietary restriction. This review focuses on the molecular mechanisms underlying the mitochondrial protective effects of resveratrol, which could be exploited for the prevention or amelioration of age-related diseases in the elderly.

  • 出版日期2011-7