Detection and characterization of early malignancy in the esophagus: What is the best management algorithm?

作者：Singh Rajvinder^*; Yeap Sze Pheh; Cheong Kuan Loong

来源：Best Practice & Research in Clinical Gastroenterology, 2015, 29(4): 533-544.

DOI：10.1016/j.bpg.2015.06.004

• Barrett's esophagus
• Intestinal metaplasia
• Seattle protocol
• Image-enhanced endoscopy
• Chromoendoscopy
• Narrow band imaging
• Autofluorescence imaging
• Confocal laser endomicroscopy
• Early esophageal adenocarcinoma
• Radiofrequency ablation
• Argon plasma coagulation
• Endoscopic mucosal resection

Barrett's esophagus is a known precursor for esophageal adenocarcinoma. Early detection of dysplasia provides a window of opportunity for curative intervention. Several image-enhanced technologies have been developed to improve visualization of neoplasia. These however have not been found to be superior to the standard four quadrant random biopsy protocol. Patients are risk-stratified based on the degree of dysplasia found on biopsies and undergo either surveillance or treatment. Endoscopic therapy has become the mainstay of treatment for early neoplasia.

• 出版日期2015-8