Medical management of early pregnancy failure: How to treat and what to expect

作者：Dempsey Angela^*; Davis Anne

来源：Seminars in Reproductive Medicine, 2008, 26(5): 401-410.

DOI：10.1055/s-0028-1087106

• early pregnancy failure
• miscarriage
• spontaneous abortion
• incomplete abortion
• misoprostol

Medical management is gaining acceptance as a treatment option for women with early pregnancy failure (EPF). We reviewed randomized trials comparing misoprostol for EPF with surgical (dilation and curettage) or expectant management. Overall, similar to 85% of women with EPF can expect complete uterine evacuation after one or two doses of 600 or 800 mu g misoprostol without surgery. Medical management is safe. As with Surgical therapy, serious complications are rare. Women undergoing medical management of EPF may expect moderate pain and bleeding for several days, which may persist for 2 weeks or longer. Side effects associated with misoprostol are common; however, acceptability of medical management remains high.

• 出版日期2008-9