An Enantiopure 5,5-Bitetracene

作者：Toyota Shinji^*; Miyaji Ryutaro; Yamamoto Yuta; Inoue Masataka; Wakamatsu Kan; Iwanaga Tetsuo

来源：European Journal of Organic Chemistry, 2015, 2015(35): 7648-7651.

DOI：10.1002/ejoc.201501135

• Biaryls
• Chiral resolution
• Circular dichroism
• Density functional calculations
• Absolute stereochemistry

Two 5,5-bitetracene derivatives were synthesized from tetracenone in three steps as novel axially chiral biaryls. The enantiomers of 12,12-bis(phenylethynyl) derivative were successfully resolved by chiral HPLC. Their absolute stereochemistry was determined by theoretical calculations of the CD spectra using the time-dependent (TD) DFT method.

• 出版日期2015-12