Mitochondrial genome variability within the Candida parapsilosis species complex

作者：Valach Matus^*; Pryszcz Leszek P; Tomaska Lubomir; Gacser Attila; Gabaldon Toni; Nosek Jozef

来源：Mitochondrion, 2012, 12(5): 514-519.

DOI：10.1016/j.mito.2012.07.109

• Candida
• Mitochondrial DNA
• Recombination
• Telomere Genetic diversity
• Evolution

Candida parapsitosis species complex includes three closely related species, namely C. parapsilosis (sensu stricto). C. orthopsitosis. and C. metapsilosis. Unlike most other yeast lineages, members of this species complex possess a linear mitochondrial genome. Yet, its circularized mutant form was identified in strains of C orthopsilosis and C. metapsilosis. To investigate the underlying variability, we performed comparative analyses of the complete mitochondrial DNA sequences in a collection of strains. Our results demonstrate that in contrast to C. parapsitosis and C. metapsilosis, C orthopsilosis exhibits remarkably high nucleotide diversity whose pattern is consistent with intraspecific genetic exchange.

• 出版日期2012-9