摘要

In nature, the macromolecular organization of multienzyme complexes has important implications for the specificity, regulation and overall efficiency of biochemical reactions. Artificial multienzyme complexes mimicking natural multienzyme organization would represent promising biocatalysts. In this review, we will give an overview of current developments and successes in the field of multienzyme complex formation using DNA scaffolds, synthetic protein scaffolds and self-assembling protein scaffolds.

  • 出版日期2012-11