A new self-expanding transcatheter aortic valve for transapical implantation - first in man implantation of the JenaValve (TM)

作者：Kempfert Joerg^*; Rastan Ardawan J; Mohr Friedrich W; Walther Thomas

来源：European Journal of Cardio-Thoracic Surgery, 2011, 40(3): 761-763.

DOI：10.1016/j.ejcts.2010.12.063

• Aortic valve replacement
• Minimal invasive surgery
• Transcatheter valves

Transapical aortic valve implantation (TA-AVI) has evolved as a routine procedure to treat selected high-risk elderly patients. In the vast majority, the balloon-expandable SAPIEN (TM) prosthesis has been used for TA-AVI. The new JenaValve (TM) prosthesis is designed for antegrade transapical implantation and consists of a self-expandable Nitinol (TM) stent with a porcine tissue-prosthesis mounted on a sheath-less delivery catheter. Key features of the device are three 'positioning feelers' facilitating intuitive 'self-positioning' valve implantation. The JenaValve (TM) concept results in a subcoronary valve position with an anatomically correct valve rotation relying on axial in addition to radial fixation by the three Nitinol (TM) 'feelers' embracing the native valve leaflets. Here, we report the successful first-in-man implantation in an elderly high-risk patient using a transapical off-pump approach. The JenaValve (TM) demonstrated proof of concept and a good functional result immediately after deployment and at 12-months' follow-up.

• 出版日期2011-9